AB SCIEX QTRAP-5500 Linear Ion Mds Qtrap Q1 1015017 Q3 1015018

( Brand: Ab Sciex ), ( Manufacturer Part Number: QTRAP-5500 ), ( Model: QTRAP 5500 ), ( Part Type: Linear )

Review AB SCIEX Qtrap Linear Ion Quadrupole Q1 Q3 Mds Working

The **AB Sciex QTrap 5500** is a high-performance, triple quadrupole-linear ion trap mass spectrometer engineered to deliver unparalleled sensitivity, selectivity, and robustness for a wide range of analytical applications, from quantitative bioanalysis and environmental monitoring to forensic toxicology and pharmaceutical research. As part of the advanced **QTRAP** (Quadrupole Linear Ion Trap) platform, this system combines the precision of a triple quadrupole configuration with the versatility of a linear ion trap (Q3), enabling researchers to perform both targeted MRM (Multiple Reaction Monitoring) and untargeted discovery experiments with exceptional efficiency. The **Q1 (1015017)** and **Q3 (1015018)** components are critical to its functionality, where Q1 acts as a high-resolution mass filter for precursor ion selection, while Q3 operating as either a linear ion trap or a high-sensitivity triple quadrupole facilitates advanced fragmentation techniques such as **MRM, enhanced product ion (EPI), enhanced multiple charge (EMC), and enhanced resolution (ER) scans**. This dual-mode capability allows users to switch seamlessly between high-throughput quantitative analysis and detailed structural elucidation, making the QTrap 5500 ideal for complex sample matrices where both speed and depth of information are required.

At the heart of the QTrap 5500 s performance lies its **Turbo V ion source**, which employs a proprietary gas curtain interface to minimize matrix interference while maximizing ion transmission efficiency. This design ensures consistent signal stability across a broad dynamic range, even in challenging samples like biological fluids, soil extracts, or industrial effluents. The system s **Turbo V source** is complemented by a **high-capacity linear ion trap (Q3)** that can trap and fragment ions with exceptional sensitivity, enabling the detection of low-abundance analytes down to sub-picomolar concentrations. The **Q1 quadrupole**, with its precise mass filtering capabilities, ensures that only the selected precursor ions enter the trap, reducing background noise and enhancing the specificity of the analysis. Together, these components enable the QTrap 5500 to achieve **low parts-per-billion (ppb) to parts-per-trillion (ppt) detection limits**, making it indispensable for regulatory compliance, clinical diagnostics, and environmental safety assessments.

Beyond its analytical power, the QTrap 5500 is designed with **user-friendly operation and advanced automation** in mind. The system integrates seamlessly with **Analyst Software**, a comprehensive platform that supports method development, data acquisition, and sophisticated data processing tools such as **Quantitative Data Analysis (QDA), PeakView , and MasterView **. These features enable researchers to perform **MRM-based quantitation with high accuracy**, while also leveraging **information-dependent acquisition (IDA)** for automated switching between MRM and EPI scans, optimizing workflow efficiency. The instrument s **high-speed scanning capabilities** achieving up to **1,000 transitions per second** allow for rapid full-scan surveys and targeted quantitation, reducing analysis times without compromising sensitivity. Additionally, the QTrap 5500 s **compact footprint and modular design** make it suitable for both research laboratories and clinical settings, where space and workflow integration are critical considerations.

For applications requiring **ultra-high resolution and mass accuracy**, the system can be configured with **enhanced resolution (ER) mode**, where Q1 operates in a high-resolution scanning format to distinguish isobaric interferences with mass accuracies better than **5 ppm**. This is particularly valuable in **drug metabolism studies, metabolomics, and proteomics**, where distinguishing between structurally similar compounds is essential. The **linear ion trap (Q3)** further enhances the system s capabilities by enabling **MS experiments**, allowing for the unambiguous identification of complex fragmentation patterns. Whether conducting **targeted quantitation, metabolite profiling, or structural characterization**, the QTrap 5500 provides the flexibility to adapt to diverse analytical challenges with confidence.

Built with **durability and reliability in mind**, the QTrap 5500 incorporates **AB Sciex s proprietary technologies**, including **Turbo V ion optics, advanced vacuum systems, and self-diagnostic tools**, to ensure minimal downtime and optimal performance over extended periods. The system s **automated calibration and maintenance routines** simplify routine upkeep, while its **compatibility with a wide range of sample introduction techniques** including **LC-MS/MS, GC-MS/MS, and direct infusion** expands its versatility across different analytical disciplines. Whether used for **pharmaceutical development, environmental monitoring, or forensic analysis**, the QTrap 5500 represents a cutting-edge solution for laboratories demanding both **high-throughput quantitation and deep structural insights** in a single, integrated platform. With its unmatched sensitivity, selectivity, and ease of use, it stands as a cornerstone instrument for modern mass spectrometry applications.

### **Pros and Cons of Buying an AB Sciex QTrap 5500 (Linear Ion Trap, Q1: 1015017, Q3: 1015018, MDS)**

#### **Pros**

1. **High Sensitivity and Detection Limits**

The QTrap 5500 is designed for ultra-sensitive detection, making it ideal for trace-level analysis in fields such as forensic toxicology, clinical diagnostics, and environmental monitoring. Its triple-quadrupole-linear ion trap (QqQLIT) configuration enhances sensitivity compared to traditional triple-quadrupole systems.

2. **Versatility in Analysis Modes**

- **MRM (Multiple Reaction Monitoring)** for high specificity and quantitation.

- **Enhanced Product Ion (EPI) and Enhanced Multiple Reaction Monitoring (eMRM)** for structural confirmation and qualitative analysis.

- **Information-Dependent Acquisition (IDA)** for targeted and untargeted workflows.

This flexibility allows researchers to switch between quantitative and qualitative analyses without major instrument changes.

3. **Linear Ion Trap (Q3) for Structural Elucidation**

The presence of a linear ion trap in Q3 enables **MS experiments**, which are crucial for confirming the identity of complex molecules, distinguishing isomers, and resolving co-eluting compounds. This is particularly valuable in metabolomics, drug discovery, and forensic chemistry.

4. **High Throughput and Speed**

The QTrap 5500 is optimized for faster cycle times compared to traditional triple-quadrupole systems, making it suitable for high-sample-throughput applications such as clinical laboratories or industrial quality control.

5. **Compatibility with AB Sciex s Software and Workflows**

The instrument integrates seamlessly with **Analyst Software** and **Sciex cloud-based solutions (e.g., Cloud DDA, Cloud MRM)**, enabling automated method development, data processing, and reporting. This reduces manual intervention and improves reproducibility.

6. **Robust and Reliable Performance**

AB Sciex is a well-established manufacturer with a strong reputation for durable and low-maintenance mass spectrometers. The QTrap 5500 is built for long-term use with minimal downtime, supported by extensive service networks and spare parts availability.

7. **Applications Across Multiple Fields**

- **Clinical toxicology** (drug screening, therapeutic drug monitoring).

- **Forensic science** (drug analysis, poison detection).

- **Pharmaceutical research** (bioanalysis, metabolite profiling).

- **Environmental analysis** (pesticides, contaminants).

- **Food safety** (residue analysis, adulteration detection).

8. **Modularity and Upgradability**

AB Sciex offers upgrade paths for newer technologies (e.g., switching to a more advanced QTRAP model or adding new ion sources). This ensures the instrument remains relevant as analytical needs evolve.

9. **Strong User Community and Support**

AB Sciex provides extensive training, application notes, and technical support. The large user base means access to troubleshooting resources, method libraries, and peer-reviewed publications.

10. **Cost-Effective for High-Throughput Labs**

While the initial purchase price is high, the QTrap 5500 s efficiency in handling large sample volumes and its ability to perform both quantitative and qualitative analyses can reduce long-term costs compared to owning separate instruments.

---

#### **Cons**

1. **High Initial Cost**

The QTrap 5500 is an expensive instrument, with purchase prices typically ranging from **$300,000 to $500,000 **, depending on configuration and optional accessories. This can be a significant barrier for small labs or startups with limited budgets.

2. **Complexity and Steep Learning Curve**

The instrument s advanced capabilities (e.g., MS , IDA, eMRM) require trained personnel to operate effectively. New users may need extensive training, which can slow down initial productivity. Additionally, method development can be time-consuming.

3. **Maintenance and Consumables Costs**

- **Ion source cleaning** (electrospray or APCI sources degrade over time).

- **Lens and skimmer replacements** (wear and tear from sample introduction).

- **Consumables** such as spray needles, capillary tubes, and collision gases (argon).

These costs add up over time and can be a significant ongoing expense.

4. **Software Dependency**

The instrument relies heavily on **Analyst Software**, which may require periodic updates. Compatibility issues with newer operating systems or hardware can occasionally arise, and some users report occasional software glitches that may disrupt workflows.

5. **Space and Infrastructure Requirements**

The QTrap 5500 requires a dedicated, climate-controlled laboratory space with proper ventilation (for ion sources) and electrical stability. Labs with limited space or outdated infrastructure may struggle to accommodate it.

6. **Limited Open-Source or Third-Party Integration**

Unlike some open-access mass spectrometers, the QTrap 5500 is proprietary. While AB Sciex provides robust tools, users may find fewer third-party plugins or open-source alternatives compared to other platforms (e.g., Thermo Scientific or Waters).

7. **Potential for Overkill in Some Applications**

For labs performing only simple MRM-based quantitation (e.g., routine drug screening with a fixed panel of analytes), a **simpler triple-quadrupole system** (e.g., AB Sciex 4000 or 6500) may suffice. The added complexity of the QTrap 5500 s LIT may not be necessary, leading to underutilization of its advanced features.

8. **Depreciation and Obsolescence Risk**

Mass spectrometry technology evolves rapidly, and while the QTrap 5500 is still widely used, newer models (e.g., AB Sciex 6500 QTRAP) offer improved sensitivity, faster scanning speeds, and better software integration. Labs may need to upgrade within **5 10 years**, leading to depreciation costs.

9. **Sample Preparation Demands**

The instrument s high sensitivity means that **sample preparation becomes critical**. Poorly prepared samples (e.g., matrix effects, contamination) can lead to false positives/negatives or instrument fouling, requiring additional time and resources for cleanup.

10. **Service and Repair Delays**

While AB Sciex has a strong support network, service delays can occur, especially in regions with limited local service centers. Extended downtime can disrupt critical workflows in clinical or industrial settings.

---

### **Conclusion**

The **AB Sciex QTrap 5500** is a **highly capable, versatile, and sensitive mass spectrometer** that excels in applications requiring **both quantitative precision (MRM) and structural confirmation (MS )**. Its strengths lie in its **flexibility, speed, and robustness**, making it ideal for **clinical toxicology, forensic science, pharmaceutical research, and environmental monitoring**. However, its **high cost, complexity, and maintenance requirements** make it less suitable for **small labs or those with simple, high-throughput needs**.

For labs that can justify the investment and have the expertise to fully utilize its features, the QTrap 5500 is a **strong long-term choice**. Conversely, labs with **limited budgets, minimal MS expertise, or straightforward analytical needs** may find a **simpler triple-quadrupole system** or a **hybrid quadrupole-Orbitrap** (e.g., Thermo Q Exactive) to be more cost-effective.

---

### **Recommendation**

- Your lab requires **both quantitative (MRM) and qualitative (MS ) capabilities** in a single instrument.

- You work in **forensic toxicology, clinical diagnostics, drug discovery, or environmental analysis** where sensitivity and structural confirmation are critical.

- You have **dedicated personnel trained in mass spectrometry** or are willing to invest in training.

- Your budget allows for the **high upfront cost** and ongoing maintenance expenses.

- You prioritize **AB Sciex s software ecosystem** and compatibility with existing workflows.

- Your primary need is **high-throughput MRM quantitation** without MS requirements (e.g., AB Sciex 4000 or 6500).

- You work in **metabolomics or proteomics**, where a **hybrid quadrupole-Orbitrap (e.g., Thermo Q Exactive or SCIEX TripleTOF)** may offer better resolution and sensitivity.

- Your lab has **limited funding** or space constraints, making the QTrap 5500 s cost and size prohibitive.

- You prefer **open-source or more flexible software platforms** (e.g., Waters Xevo TQ-S or Shimadzu LCMS-8060).

The QTrap 5500 is a **premium instrument** that delivers **unmatched versatility** for labs needing advanced mass spectrometry. If your analytical goals align with its strengths, it is a **reliable and future-proof investment**. However, weigh the costs carefully against your lab s specific needs to ensure it remains the best choice over time.

Details:

AB Sciex QTRAP 5500 Linear Ion Quadrupole Q1 1015017 Q3 1015018 MDS Working. The physical condition is good, but there are signs of previous use and handling. Only items pictured are included: If a part is not pictured, or mentioned Above, then it included in the sale. Serial numbers or country of manufacture may vary.

Sale Details. PCB Part No: 1015018, INTERCONNECT Q3, 1015021This item is working surplus. PCB Part No: 1015017, INTERCONNECT Q1, 1015020. Part No: QTRAP 5500Installed Components.

Pictured test equipment is not included or available for sale.

part #: qtrap5500 prices

• $700.00-$140000.00

specifications industrlasemr:

• brand: Ab Sciex
• mpn: Qtrap-5500
• model: Qtrap 5500
• part type: Linear

payments industrlasemr:

• other
• wallet: Google-pay
• credit card: Visa

seller industrlasemr:

• rating: 99.6%
• city: Albuquerque, New Mexico
• # reviews: 10570

offer industrlasemr:

• started: May 28, 2026
• availAbility: In Stock
• options: Ship-to-home
• sold: 0
• quantity: 1
• best offers: True

shipping industrlasemr:

• cost: $92.58
• class: Standard
• service: FedEx Ground / FedEx Home Delivery
• type: Calculated
• transit: 4-8 Days
• carrier: FedEx

general industrlasemr:

• Medical/LAb Equipment Attachments Accessories > Lamps, Bulbs Laser Components > Laser Modules Heads
• condition: Used

returns industrlasemr:

• paid by: Buyer
• method: Money back
• policy: Returns Accepted
• time: 60 Days

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